Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | GPR174 | Q9BXC1 | 8/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL521293 | 0.91 | MAPT (0.63) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL30258446 | 0.91 | MAPT (0.63) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL8221482 | 0.88 | MAPT (0.60) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL521504 | 0.87 | MAPT (0.59) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL3927908 | 0.87 | MAPT (0.76) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL30965670 | 0.87 | MAPT (0.59) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL31487436 | 0.87 | MAPT (0.59) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL31129953 | 0.87 | MAPT (0.58) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL29094526 | 0.86 | MAPT (0.57) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL22716822 | 0.85 | MAPT (0.57) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| CN-119790057-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2025-04-08 | — | — | CN | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |