Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 18/20 | 0.46 |
| ▸ | BRD4 | O60885 | 12/20 | 0.46 |
| ▸ | BRDT | Q58F21 | 3/20 | 0.46 |
| ▸ | PDXK | O00764 | 1/20 | 0.41 |
| ▸ | WEE1 | P30291 | 1/20 | 0.41 |
| ▸ | NEK3 | P51956 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.41 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.38 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965515 | 0.98 | PLK1 (0.46) | PLK1BRD4BRDTPDXKWEE1 | |
| SCHEMBL30965655 | 0.96 | PLK1 (0.45) | PLK1BRD4BRDTPDXKWEE1 | |
| SCHEMBL30965779 | 0.94 | PLK1 (0.46) | PLK1BRD4BRDTPDXKWEE1 | |
| SCHEMBL30965520 | 0.93 | PLK1 (0.46) | PLK1BRD4BRDTPDXKWEE1 | |
| SCHEMBL30965584 | 0.93 | PLK1 (0.46) | PLK1BRD4BRDTPDXKWEE1 | |
| SCHEMBL30965742 | 0.93 | PLK1 (0.47) | PLK1BRD4BRDTPLK3PLK2 | |
| SCHEMBL30965734 | 0.93 | PLK1 (0.41) | PLK1BRD4BRDTPDXKWEE1 | |
| SCHEMBL30965567 | 0.92 | PLK1 (0.57) | PLK1BRD4BRDTPLK3PLK2 | |
| SCHEMBL30965801 | 0.92 | PLK1 (0.47) | PLK1BRD4BRDTPDXKWEE1 | |
| SCHEMBL30965683 | 0.92 | PLK1 (0.42) | PLK1BRD4BRDTPDXKWEE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |