Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25035255 | 0.95 | CRBN (0.42) | CRBNDDB1POLBGSPT1HRH3 | |
| SCHEMBL30965735 | 0.88 | CRBN (0.43) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL30965632 | 0.88 | CRBN (0.45) | CRBNDDB1POLBHRH3 | |
| SCHEMBL25035256 | 0.82 | CRBN (0.44) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL25035254 | 0.80 | CRBN (0.47) | CRBNDDB1POLBHRH3 | |
| SCHEMBL31712325 | 0.79 | CRBN (0.49) | CRBNDDB1POLB | |
| SCHEMBL30475503 | 0.78 | CRBN (0.49) | CRBNDDB1POLB | |
| SCHEMBL25822215 | 0.78 | CRBN (0.49) | CRBNDDB1POLB | |
| SCHEMBL25033945 | 0.78 | CRBN (0.41) | CRBNDDB1POLB | |
| SCHEMBL25029440 | 0.77 | CRBN (0.51) | CRBNDDB1POLBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| CN-119790057-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2025-04-08 | — | — | CN | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |