Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 16/20 | 0.50 |
| ▸ | BRD4 | O60885 | 9/20 | 0.50 |
| ▸ | BRDT | Q58F21 | 3/20 | 0.50 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.49 |
| ▸ | PLK2 | Q9NYY3 | 2/20 | 0.49 |
| ▸ | PDXK | O00764 | 1/20 | 0.49 |
| ▸ | WEE1 | P30291 | 1/20 | 0.49 |
| ▸ | NEK3 | P51956 | 1/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.49 |
| ▸ | DCLK1 | O15075 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.42 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25031124 | 0.94 | PLK1 (0.50) | PLK1BRD4BRDTPLK3PLK2 | |
| SCHEMBL30501248 | 0.94 | PLK1 (0.50) | PLK1BRD4BRDTPLK3PLK2 | |
| SCHEMBL30965637 | 0.93 | PLK1 (0.61) | PLK1BRD4BRDTPLK3RAD52 | |
| SCHEMBL30501269 | 0.92 | PLK1 (0.51) | PLK1BRD4BRDTPLK3PLK2 | |
| SCHEMBL25031022 | 0.92 | PLK1 (0.51) | PLK1BRD4BRDTPLK3PLK2 | |
| SCHEMBL25029395 | 0.91 | PLK1 (0.51) | PLK1BRD4BRDTPLK3PLK2 | |
| SCHEMBL30501324 | 0.91 | PLK1 (0.51) | PLK1BRD4BRDTPLK3PLK2 | |
| SCHEMBL25031330 | 0.91 | PLK1 (0.50) | PLK1BRD4BRDTPLK3PLK2 | |
| SCHEMBL30501234 | 0.91 | PLK1 (0.50) | PLK1BRD4BRDTPLK3PLK2 | |
| SCHEMBL30501241 | 0.91 | PLK1 (0.50) | PLK1BRD4BRDTPLK3PLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |