Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 17/20 | 0.65 |
| ▸ | BRD4 | O60885 | 2/20 | 0.65 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.65 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965599 | 0.95 | PLK1 (0.66) | PLK1BRD4BRDTRAD52ALK | |
| SCHEMBL31376455 | 0.92 | PLK1 (0.56) | PLK1BRD4BRDTRAD52ALK | |
| SCHEMBL30965665 | 0.91 | PLK1 (0.68) | PLK1BRD4BRDTRAD52ALK | |
| SCHEMBL30965589 | 0.90 | PLK1 (0.68) | PLK1BRD4BRDTRAD52ALK | |
| SCHEMBL30965717 | 0.89 | PLK1 (0.67) | PLK1BRD4BRDTRAD52ALK | |
| SCHEMBL30965654 | 0.88 | PLK1 (0.57) | PLK1BRD4BRDTRAD52ALK | |
| SCHEMBL30965614 | 0.87 | PLK1 (0.54) | PLK1BRD4BRDTRAD52 | |
| SCHEMBL30965664 | 0.87 | PLK1 (0.54) | PLK1BRD4BRDTRAD52ALK | |
| SCHEMBL30965633 | 0.87 | PLK1 (0.49) | PLK1BRD4BRDTRAD52 | |
| SCHEMBL25819069 | 0.87 | PLK1 (0.61) | PLK1BRD4BRDTRAD52ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |