Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 2/20 | 0.42 |
| ▸ | TRPC7 | Q9HCX4 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25822642 | 0.89 | MAPT (0.46) | CNR2NPC1FFAR4PTGDR2 | |
| SCHEMBL31333359 | 0.88 | TMEM97 (0.43) | TRPC3TRPC7CNR2SMN1; SMN2NPC1 | |
| SCHEMBL29013177 | 0.83 | FFAR4 (0.47) | SMN1; SMN2NPC1RAB9AFFAR4 | |
| SCHEMBL25822405 | 0.81 | FFAR4 (0.60) | FFAR4 | |
| SCHEMBL25935052 | 0.81 | MAPT (0.49) | TRPC3TRPC7CNR2NPC1FFAR4 | |
| SCHEMBL29013165 | 0.81 | GRM5 (0.48) | SMN1; SMN2NPC1FFAR4ENPP2 | |
| SCHEMBL30643706 | 0.80 | MAPT (0.45) | CNR2SMN1; SMN2NPC1PTGDR2 | |
| SCHEMBL25937000 | 0.80 | MAPT (0.44) | SMN1; SMN2FFAR4 | |
| SCHEMBL30475482 | 0.80 | MAPT (0.44) | SMN1; SMN2FFAR4 | |
| SCHEMBL25031334 | 0.80 | FFAR4 (0.47) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |