Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 18/20 | 0.79 |
| ▸ | BRD4 | O60885 | 3/20 | 0.62 |
| ▸ | BRDT | Q58F21 | 3/20 | 0.62 |
| ▸ | TTK | P33981 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487434 | 1.00 | PLK1 (0.79) | PLK1BRD4BRDTTTKRAD52 | |
| SCHEMBL1675603 | 0.94 | PLK1 (0.79) | PLK1BRD4BRDTTTKRAD52 | |
| SCHEMBL1559377 | 0.93 | PLK1 (0.69) | PLK1BRD4BRDTTTKRAD52 | |
| SCHEMBL1675596 | 0.89 | PLK1 (1.00) | PLK1BRD4BRDTRAD52 | |
| SCHEMBL1559241 | 0.85 | PLK1 (0.79) | PLK1BRD4BRDTTTK | |
| SCHEMBL1560954 | 0.85 | PLK1 (0.66) | PLK1BRD4BRDTTTKRAD52 | |
| SCHEMBL4412882 | 0.84 | PLK1 (0.79) | PLK1BRD4BRDTRAD52 | |
| SCHEMBL26814574 | 0.84 | PLK1 (0.79) | PLK1BRD4BRDTRAD52 | |
| SCHEMBL30136020 | 0.83 | PLK1 (0.79) | PLK1BRD4BRDTTTKRAD52 | |
| SCHEMBL30965740 | 0.83 | PLK1 (0.67) | PLK1BRD4BRDTTTKRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |