Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18321887 | 1.00 | PDE2A (0.54) | PDE2AALDH1A1MAPTHTR1AMEN1 | |
| SCHEMBL26915295 | 0.86 | PDE2A (0.50) | PDE2AALDH1A1MAPTHTR1AMEN1 | |
| SCHEMBL29755384 | 0.84 | PDE2A (0.44) | PDE2AHTR1ADAO | |
| SCHEMBL18321910 | 0.84 | PDE2A (0.44) | PDE2AHTR1ADAO | |
| SCHEMBL28745430 | 0.80 | PDE2A (0.54) | PDE2AMAPTHTR1A | |
| SCHEMBL4635224 | 0.79 | PDE2A (0.47) | PDE2AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4635226 | 0.79 | PDE2A (0.47) | PDE2AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28770910 | 0.76 | PDE2A (0.50) | PDE2AHTR1ATSHR | |
| SCHEMBL26915320 | 0.76 | PDE2A (0.42) | PDE2AHTR1AMEN1KMT2ATSHR | |
| SCHEMBL8251778 | 0.76 | PDE2A (0.44) | PDE2AALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024120378-A2 | TRIAZOLE COMPOUNDS, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-13 | — | — | WO | disclosed |