Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14997813 | 1.00 | DAO (0.37) | DAORXRAGRIN1GRIN2B | |
| SCHEMBL25949376 | 0.83 | DAO (0.38) | DAO | |
| SCHEMBL21224525 | 0.81 | ALOX5AP (0.31) | — | |
| SCHEMBL29421579 | 0.81 | ALOX5AP (0.31) | — | |
| SCHEMBL30885009 | 0.77 | DAO (0.35) | DAO | |
| SCHEMBL27107683 | 0.76 | ALOX5AP (0.38) | — | |
| SCHEMBL25928183 | 0.76 | ALOX5AP (0.31) | — | |
| SCHEMBL1098374 | 0.75 | DAO (0.39) | DAO | |
| SCHEMBL25928128 | 0.74 | DAO (0.33) | DAO | |
| SCHEMBL18306471 | 0.73 | PIK3CA (0.36) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618974-A1 | OREXIN RECEPTOR AGONISTS | Merck Sharp & Dohme LLC (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107615-A1 | OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-05-23 | — | — | WO | disclosed |