SCHEMBL30967424

SCHEMBL30967424

O=C(/C=C/c1ccc2noc(-c3ccc(-c4ccncc4)cc3)c2c1)NO

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IP6K1 Q92551 12/20 0.63
IP6K2 Q9UHH9 11/20 0.63
IP6K3 Q96PC2 10/20 0.63
ALDH1A1 P00352 5/20 0.59
HTT P42858 2/20 0.59
LMNA P02545 1/20 0.59
GAA P10253 1/20 0.47
TBK1 Q9UHD2 1/20 0.47
KDM4E B2RXH2 4/20 0.47
MEN1 O00255 3/20 0.47
POLB P06746 3/20 0.47
KMT2A Q03164 3/20 0.47
MAPT P10636 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
NPC1 O15118 2/20 0.47
HPGD P15428 1/20 0.47
RAB9A P51151 1/20 0.47
PTK2B Q14289 1/20 0.47
HDAC1 Q13547 2/20 0.46
HDAC4 P56524 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30967412 0.89 IP6K1 (0.75) IP6K1IP6K2IP6K3ALDH1A1HTT
SCHEMBL30967428 0.88 IP6K1 (0.65) IP6K1IP6K2IP6K3ALDH1A1HTT
SCHEMBL30967421 0.85 IP6K1 (0.64) IP6K1IP6K2IP6K3ALDH1A1HTT
SCHEMBL30967422 0.84 IP6K1 (0.57) IP6K1IP6K2IP6K3ALDH1A1HTT
SCHEMBL30967417 0.83 IP6K1 (0.56) IP6K1IP6K2IP6K3ALDH1A1HTT
SCHEMBL30967416 0.82 IP6K1 (0.66) IP6K1IP6K2IP6K3ALDH1A1HTT
SCHEMBL30967418 0.82 IP6K1 (0.57) IP6K1IP6K2IP6K3ALDH1A1HTT
SCHEMBL30967419 0.81 IP6K1 (0.56) IP6K1IP6K2IP6K3ALDH1A1HTT
SCHEMBL30967425 0.80 IP6K1 (0.58) IP6K1IP6K2IP6K3ALDH1A1HTT
SCHEMBL25990260 0.77 IP6K1 (1.00) IP6K1IP6K2IP6K3ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118459418-B Hydroxamic acid HDAC inhibitor and application thereof in preparation of antitumor drugs 河北中医药大学 2025-04-08 CN disclosed
CN-118459418-A Hydroxamic acid HDAC inhibitor and application thereof in preparation of antitumor drugs 河北中医药大学 2024-08-09 CN disclosed