Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNG | P07510 | 1/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CHRND | Q07001 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 4/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30521629 | 0.86 | SLC6A4 (0.40) | SLC6A4SLC6A3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL15199126 | 0.86 | SLC6A4 (0.40) | SLC6A4SLC6A3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL25349402 | 0.86 | SLC6A4 (0.40) | SLC6A4SLC6A3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL15199129 | 0.86 | SLC6A4 (0.40) | SLC6A4SLC6A3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL12672112 | 0.83 | SLC6A4 (0.37) | SLC6A4SLC6A3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL332828 | 0.83 | SLC6A4 (0.37) | SLC6A4SLC6A3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL571927 | 0.80 | CHRNA1 (0.37) | SLC6A4SLC6A3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL10270830 | 0.79 | PDE4A (0.35) | SLC6A4SLC6A3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL15200302 | 0.79 | KDM1A (0.38) | SLC6A4SLC6A3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL10270571 | 0.79 | PDE4A (0.35) | SLC6A4SLC6A3CHRNA1CHRNGCHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |