Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 5/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237584 | 1.00 | EPAS1 (0.41) | EPAS1DRD1BRD4VEGFASLC22A12 | |
| SCHEMBL29336696 | 0.92 | EPAS1 (0.38) | EPAS1DRD1BRD4VEGFASLC22A12 | |
| SCHEMBL29338274 | 0.89 | SLC22A12 (0.38) | EPAS1DRD1BRD4VEGFASLC22A12 | |
| SCHEMBL30285554 | 0.89 | SLC22A12 (0.38) | EPAS1DRD1BRD4VEGFASLC22A12 | |
| SCHEMBL30938241 | 0.83 | DRD1 (0.41) | EPAS1DRD1HAO1PRKCQ | |
| SCHEMBL27275534 | 0.83 | DRD1 (0.41) | EPAS1DRD1HAO1PRKCQ | |
| SCHEMBL27382323 | 0.83 | DRD1 (0.40) | EPAS1DRD1VEGFASLC22A12HAO1 | |
| SCHEMBL31108580 | 0.82 | PRKCQ (0.36) | EPAS1DRD1VEGFASLC22A12HAO1 | |
| SCHEMBL27266377 | 0.82 | PRKCQ (0.36) | EPAS1DRD1VEGFASLC22A12HAO1 | |
| SCHEMBL30750171 | 0.81 | PRKCQ (0.38) | EPAS1DRD1VEGFASLC22A12HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |