Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 7/20 | 0.49 |
| ▸ | RHEB | Q15382 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.40 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | VEGFA | P15692 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | DHPS | P49366 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237661 | 1.00 | EPAS1 (0.49) | EPAS1RHEBBRD4EGFRERBB2 | |
| SCHEMBL30967840 | 0.82 | PRKCQ (0.47) | EPAS1RHEBBRD4EGFRERBB2 | |
| SCHEMBL27275422 | 0.82 | EPAS1 (0.49) | EPAS1RHEBBRD4EGFRERBB2 | |
| SCHEMBL27275421 | 0.82 | PRKCQ (0.47) | EPAS1RHEBBRD4EGFRERBB2 | |
| SCHEMBL29336676 | 0.80 | BRD4 (0.45) | EPAS1RHEBBRD4EGFRERBB2 | |
| SCHEMBL29337971 | 0.80 | BRD4 (0.46) | EPAS1RHEBBRD4EGFRERBB2 | |
| SCHEMBL30967796 | 0.80 | BRD4 (0.44) | EPAS1RHEBBRD4EGFRERBB2 | |
| SCHEMBL30938228 | 0.80 | F10 (0.46) | RHEB | |
| SCHEMBL29237564 | 0.80 | BRD4 (0.44) | EPAS1RHEBBRD4EGFRERBB2 | |
| SCHEMBL30967931 | 0.80 | BRD4 (0.46) | EPAS1RHEBBRD4EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |