Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | PREP | P48147 | 4/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967988 | 1.00 | CHRM2 (0.53) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL30068303 | 0.91 | CHRM2 (0.58) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL4312871 | 0.91 | CHRM2 (0.58) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL19728175 | 0.85 | CHRM2 (0.51) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL17592860 | 0.85 | CHRM2 (0.51) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL19734273 | 0.85 | CHRM2 (0.51) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL17592862 | 0.85 | CHRM2 (0.51) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL31341776 | 0.81 | CHRM2 (0.54) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL31390583 | 0.81 | CHRM2 (0.54) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL25010681 | 0.80 | CHRM2 (0.75) | CHRM2CHRM1CHRM3PREPHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |