Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.68 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.68 |
| ▸ | PREP | P48147 | 4/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL14919387 | 0.98 | CHRM2 (0.66) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL12345350 | 0.96 | CHRM2 (0.68) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL20635190 | 0.96 | CHRM2 (0.68) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL5198741 | 0.96 | CHRM2 (0.68) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL12461664 | 0.94 | CHRM2 (0.65) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL14545684 | 0.94 | CHRM2 (0.65) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL25010681 | 0.94 | CHRM2 (0.75) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL2123260 | 0.94 | CHRM2 (0.75) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL22341040 | 0.86 | CHRM2 (0.71) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL26251587 | 0.86 | CHRM2 (0.71) | CHRM2CHRM1CHRM3PREPHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |