⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11740480 | 0.85 | — | — | |
| SCHEMBL196024 | 0.78 | — | — | |
| SCHEMBL5697745 | 0.78 | — | — | |
| Water SCHEMBL6010194 | 0.76 | POLB (0.50) | — | |
| SCHEMBL11436434 | 0.74 | — | — | |
| SCHEMBL4586681 | 0.74 | — | — | |
| SCHEMBL9677305 | 0.74 | — | — | |
| SCHEMBL12892263 | 0.74 | — | — | |
| SCHEMBL3096825 | 0.72 | — | — | |
| SCHEMBL8430579 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107641202-A | A kind of Cu (I) base fluorescence metal organic backbone and preparation method and application | 中北大学 | 2018-01-30 | — | — | CN | claimed |
| US-5614533-A | Substituted pipecolinic acid derivatives as HIV protease inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH, INC. (CA) | 1997-03-25 | — | — | US | claimed |
| EP-0560268-B1 | Substituted pipecolinic acid derivatives as HIV protease inhibitors | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-01-04 | — | — | EP | claimed |
| EP-0560268-A1 | Substituted pipecolinic acid derivatives as HIV protease inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-15 | — | — | EP | claimed |
| EP-2945950-B1 | ISOMANNIDE DERIVATIVES AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | SANOFI SA (FR) | 2017-03-01 | — | — | EP | disclosed |
| CN-102702147-B | The application of andrographolide analog and treatment thereof | 辽宁利锋科技开发有限公司 | 2016-06-08 | — | — | CN | disclosed |
| US-20150150893-A1 | ANDROGRAPHOLIDE ANALOGS AND THEIR USE FOR MEDICATION | LIAONING LIFENG SCIENT & TECHNOLOGY DEV COMPANY LTD (CN) | 2015-06-04 | — | — | US | disclosed |
| EP-1764650-B1 | Photosensitive composition, and lithographic printing plate precursor and image-recording method using the same | FUJIFILM CORP (JP) | 2013-02-27 | — | — | EP | disclosed |
| CN-102702147-A | Andrographolide analogue and application of andrographolide analogue to treatment | LIAONING LIFENG TECHNOLOGY DEV CO LTD | 2012-10-03 | — | — | CN | disclosed |
| US-20100233415-A1 | OPTICAL RECORDING MEDIUM AND AZO METAL CHELATE COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-1997856-A1 | OPTICAL RECORDING MEDIUM AND AZO METAL CHELATE COMPOUND | Mitsui Chemicals, Inc. (JP) | 2008-12-03 | — | — | EP | disclosed |
| CN-1543346-A | Novel compounds | ʷ��˿�������ȳ�ķ����˾ | 2004-11-03 | — | — | CN | disclosed |
| US-6765003-B1 | ANTICARCINOGENIC, ANTITUMOR, AND ANTIMETASTASIS AGENTS; RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPOROSIS, MULTIPLE SCLEROSIS, STROKE, ARTERIOSCLEROSIS, | PHARMACIA ITALIA, SPA (IT) | 2004-07-20 | — | — | US | disclosed |
| EP-1200398-A1 | 3-ARYLSULFONYL-2-(SUBSTITUTED METHYL)PROPANOIC ACID DERIVATES AS MATRIX METALLOPROTEINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001005756-A1 | 3-ARYLSULFONYL-2-(SUBSTITUTED METHYL)PROPANOIC ACID DERIVATES AS MATRIX METALLOPROTEINASE INHIBITORS | PHARMACIA & UPJOHN SPA (IT) | 2001-01-25 | — | — | WO | disclosed |
| US-5807870-A | SIDE EFFECT REDUCTION | BIOMEGA BOEHRINGER INGELHEIM RESEARCH LTD. (CA) | 1998-09-15 | — | — | US | disclosed |
| EP-0643702-B1 | 4-PYRIMIDINE SULFENAMIDES AND THEIR USE IN RUBBER | MONSANTO CO (US) | 1997-01-02 | — | — | EP | disclosed |
| CN-1079482-A | 4-pyrimidine sulfinyl amine and the application in rubber thereof | MONSANTO CO (US) | 1993-12-15 | — | — | CN | disclosed |
| US-4057634-A | Antiprotozoal(1-alkyl-5-nitro-imidazolyl-2-alkyl)-pyridazines | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-11-08 | — | — | US | disclosed |
| US-3991191-A | Antiprotozoal (1-alkyl-5-nitro-imidazolyl-2-alkyl)-pyrimidines | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | disclosed |