SCHEMBL30968541

SCHEMBL30968541

CC(C)(C)OC(=O)N1C2CCC1CN(c1cc3c(cc1F)CC(NC(=O)OCc1ccccc1)CC3)C2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
ACHE P22303 2/20 0.47
SCN9A Q15858 1/20 0.41
RORC P51449 3/20 0.41
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
CTSK P43235 1/20 0.41
HDAC8 Q9BY41 1/20 0.40
GPR119 Q8TDV5 1/20 0.40
AGTR2 P50052 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
JAK1 P23458 1/20 0.38
MEN1 O00255 2/20 0.38
GPR55 Q9Y2T6 2/20 0.38
TSHR P16473 1/20 0.38
HDAC1 Q13547 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20722804 1.00 CA1 (0.47) CA1CA2ACHESCN9ARORC
SCHEMBL30060154 0.91 CA1 (0.47) CA1CA2ACHESCN9ARORC
SCHEMBL20722441 0.91 CA1 (0.47) CA1CA2ACHESCN9ARORC
SCHEMBL20722462 0.89 CA1 (0.48) CA1CA2ACHESCN9ARORC
SCHEMBL30059927 0.89 CA1 (0.48) CA1CA2ACHESCN9ARORC
SCHEMBL20722755 0.86 CA1 (0.49) CA1CA2ACHESCN9ACTSL
SCHEMBL30059971 0.86 CA1 (0.49) CA1CA2ACHESCN9ACTSL
SCHEMBL30968503 0.86 CA1 (0.51) CA1CA2ACHESCN9ARORC
SCHEMBL20722366 0.86 CA1 (0.51) CA1CA2ACHESCN9ARORC
SCHEMBL30968530 0.85 CA1 (0.45) CA1CA2ACHESCN9ARORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112867712-B Carboxamide as ubiquitin-specific protease inhibitor 瓦洛早期发现股份有限公司 2024-07-16 CN disclosed