Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28562423 | 1.00 | KIT (0.41) | KITGPR119GRIA1GBA1TLR9 | |
| SCHEMBL20731149 | 1.00 | KIT (0.41) | KITGPR119GRIA1GBA1TLR9 | |
| SCHEMBL20722357 | 0.85 | MAPK1 (0.31) | — | |
| SCHEMBL20732039 | 0.81 | KIT (0.42) | KITGPR119GRIA1TLR9DPP4 | |
| SCHEMBL20723028 | 0.81 | KIT (0.42) | KITGPR119GRIA1TLR9DPP4 | |
| SCHEMBL30059936 | 0.81 | KIT (0.42) | KITGPR119GRIA1TLR9DPP4 | |
| SCHEMBL28913737 | 0.81 | MAP4K4 (0.51) | KITGPR119MAP4K4SMARCA2SMARCA4 | |
| SCHEMBL20732187 | 0.81 | MAP4K4 (0.51) | KITGPR119MAP4K4SMARCA2SMARCA4 | |
| SCHEMBL30060039 | 0.81 | MAP4K4 (0.51) | KITGPR119MAP4K4SMARCA2SMARCA4 | |
| SCHEMBL20731975 | 0.81 | HTT (0.41) | KITGPR119DPP4SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |