Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 15/20 | 0.64 |
| ▸ | HSP90AB1 | P08238 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.44 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930364 | 0.83 | HPGD (0.65) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL5006001 | 0.76 | HSP90AB1 (0.71) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL14344600 | 0.75 | KDM4E (0.69) | HSP90AA1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL12180147 | 0.75 | HSP90AA1 (0.78) | HSP90AA1HSP90AB1KDM4EMAPTALDH1A1 | |
| SCHEMBL13983078 | 0.74 | POLB (0.61) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL4939682 | 0.74 | ESR1 (0.48) | HSP90AA1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL8931049 | 0.73 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1KDM4EALDH1A1ESR1 | |
| SCHEMBL12045736 | 0.73 | HSP90AA1 (0.72) | HSP90AA1HSP90AB1KDM4EMAPTALDH1A1 | |
| SCHEMBL8931044 | 0.73 | HSP90AA1 (0.84) | HSP90AA1HSP90AB1KDM4EMAPTALDH1A1 | |
| SCHEMBL8930502 | 0.72 | HPGD (0.61) | HSP90AA1KDM4EMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118356493-A | Application of PDK1 protein or coding gene thereof as target spot in preparation of medicines for treating systemic lupus erythematosus | 中南大学湘雅二医院 | 2024-07-19 | — | — | CN | claimed |
| CN-118045188-A | Application of PDK1 as target in preventing or treating diabetes | 中南大学湘雅二医院 | 2024-05-17 | — | — | CN | claimed |
| CN-119732939-A | Use of Etalocib in preparing medicine for resisting gram positive bacteria infection | 华中科技大学协和深圳医院 | 2025-04-01 | — | — | CN | disclosed |
| CN-118045188-A | Application of PDK1 as target in preventing or treating diabetes | 中南大学湘雅二医院 | 2024-05-17 | — | — | CN | disclosed |