Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30969294 | 0.87 | POLB (0.70) | NPC1ALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL3216795 | 0.87 | ATM (0.70) | NPC1ALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL16900138 | 0.87 | POLB (0.63) | NPC1ALDH1A1KDM4ETHRBPOLB | |
| Hydrochloric Acid SCHEMBL30969246 | 0.84 | NPC1 (0.73) | NPC1ALDH1A1KDM4ETHRBPOLB | |
| SCHEMBL5925560 | 0.84 | NPC1 (0.73) | NPC1ALDH1A1KDM4ETHRBPOLB | |
| SCHEMBL1409462 | 0.84 | KDM4E (0.71) | NPC1ALDH1A1KDM4ETHRBPOLB | |
| SCHEMBL22407743 | 0.83 | KDM4E (0.69) | NPC1ALDH1A1KDM4ETHRBPOLB | |
| SCHEMBL4777614 | 0.83 | KDM4E (0.69) | NPC1ALDH1A1KDM4ETHRBPOLB | |
| SCHEMBL10210776 | 0.82 | NPC1 (0.74) | NPC1ALDH1A1KDM4ETHRBPOLB | |
| SCHEMBL10917054 | 0.82 | KDM4E (0.73) | NPC1ALDH1A1KDM4ETHRBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642766-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145585-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-04 | — | — | WO | disclosed |