Ciclopirox

Ciclopirox

SCHEMBL30969895

Cc1cc(C2CCCCC2)n(O)c(=O)c1.NO

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.94
KDM4B O94953 1/20 0.94
CHRM1 P11229 1/20 0.94
TBXA2R P21731 1/20 0.94
ADRA1A P35348 1/20 0.94
DOHH Q9BU89 1/20 0.94
KDM4E B2RXH2 1/20 0.81
LMNA P02545 1/20 0.81
TP53 P04637 1/20 0.81
CYP1A2 P05177 1/20 0.81
ALOX12 P18054 1/20 0.81
MAPK1 P28482 1/20 0.81
SMN1; SMN2 Q16637 1/20 0.81
HIF1A Q16665 1/20 0.81
TDP1 Q9NUW8 1/20 0.81
IDH1 O75874 11/20 0.38
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ciclopirox SCHEMBL34424 0.97 NR1I2 (1.00) NR1I2KDM4BCHRM1TBXA2RADRA1A
Ciclopirox SCHEMBL1818483 0.97 NR1I2 (1.00) NR1I2KDM4BCHRM1TBXA2RADRA1A
Ciclopirox SCHEMBL21571455 0.91 NR1I2 (0.83) NR1I2KDM4BCHRM1TBXA2RADRA1A
Ciclopirox SCHEMBL514700 0.90 KDM4E (1.00) NR1I2KDM4BCHRM1TBXA2RADRA1A
Ciclopirox SCHEMBL66960 0.90 KDM4E (1.00) NR1I2KDM4BCHRM1TBXA2RADRA1A
Ciclopirox SCHEMBL1411724 0.90 KDM4E (1.00) NR1I2KDM4BCHRM1TBXA2RADRA1A
Ciclopirox SCHEMBL6264129 0.85 KDM4E (0.90) NR1I2KDM4BCHRM1TBXA2RADRA1A
Ciclopirox SCHEMBL28169345 0.85 KDM4E (0.90) NR1I2KDM4BCHRM1TBXA2RADRA1A
Ciclopirox SCHEMBL2118898 0.83 NR1I2 (0.74) NR1I2KDM4BCHRM1TBXA2RADRA1A
SCHEMBL10726807 0.82 NR1I2 (0.73) NR1I2KDM4BCHRM1TBXA2RADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626862-A1 PROCESS FOR THE PREPARATION OF N-HYDROXYPYRIDONE COMPOUNDS CLARIANT INTERNATIONAL LTD (CH) 2025-10-08 EP claimed
WO-2024115319-A1 PROCESS FOR THE PREPARATION OF N-HYDROXYPYRIDONE COMPOUNDS CLARIANT INTERNATIONAL LTD (CH) 2024-06-06 WO claimed
EP-4626862-A1 PROCESS FOR THE PREPARATION OF N-HYDROXYPYRIDONE COMPOUNDS CLARIANT INTERNATIONAL LTD (CH) 2025-10-08 EP disclosed
WO-2024115319-A1 PROCESS FOR THE PREPARATION OF N-HYDROXYPYRIDONE COMPOUNDS CLARIANT INTERNATIONAL LTD (CH) 2024-06-06 WO disclosed