Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | GPR183 | P32249 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338476 | 0.85 | TTR (0.56) | KDM4EALDH1A1TTRGPR183CA12 | |
| SCHEMBL2871517 | 0.85 | TTR (0.56) | KDM4EALDH1A1TTRGPR183CA12 | |
| SCHEMBL6071506 | 0.84 | KDM4E (0.83) | KDM4EALDH1A1TTRAPPPTPN1 | |
| SCHEMBL6349789 | 0.84 | DYRK1A (0.51) | KDM4EALDH1A1GPR183MAPTDYRK1A | |
| SCHEMBL6349783 | 0.84 | DYRK1A (0.51) | KDM4EALDH1A1GPR183MAPTDYRK1A | |
| SCHEMBL30970380 | 0.84 | KDM4E (0.83) | KDM4EALDH1A1TTRAPPPTPN1 | |
| SCHEMBL2717774 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1TTRAPPGPR183 | |
| SCHEMBL2717768 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1TTRAPPGPR183 | |
| SCHEMBL19805778 | 0.82 | KDM4E (0.53) | KDM4EGPR183MAPTSMN1; SMN2DYRK1A | |
| SCHEMBL21962337 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1TTRAPPGPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626870-A1 | NONCOVALENT KEAP1-NRF2 SMALL-MOLECULE INHIBITORS | University of Copenhagen (DK) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024115641-A1 | NONCOVALENT KEAP1-NRF2 SMALL-MOLECULE INHIBITORS | UNIVERSITY OF COPENHAGEN (DK) | 2024-06-06 | — | — | WO | disclosed |