Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 8/20 | 0.51 |
| ▸ | ACACB | O00763 | 2/20 | 0.49 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27229616 | 1.00 | NR1H2 (0.55) | NR1H2ESR2F10ACACBABHD6 | |
| SCHEMBL29950478 | 0.84 | F10 (0.52) | F10ACACBABHD6HRH3 | |
| SCHEMBL6189777 | 0.84 | F10 (0.66) | NR1H2ESR2F10ABHD6GPR119 | |
| SCHEMBL27229597 | 0.82 | F10 (0.50) | F10ACACBABHD6HRH3 | |
| SCHEMBL30924593 | 0.82 | F10 (0.50) | F10ACACBABHD6HRH3 | |
| SCHEMBL6187650 | 0.81 | NR1H2 (0.65) | NR1H2ESR2F10ACACBABHD6 | |
| SCHEMBL13097234 | 0.80 | ESR2 (0.56) | NR1H2ESR2F10ACACBABHD6 | |
| SCHEMBL18209393 | 0.80 | NR1H2 (0.63) | NR1H2ESR2F10HRH3 | |
| SCHEMBL6189797 | 0.80 | NR1H2 (0.63) | NR1H2ESR2F10ABHD6GPR119 | |
| SCHEMBL1266229 | 0.80 | NR1H2 (0.63) | NR1H2ESR2F10ABHD6GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956996-A | Compounds and methods for YAP/TEAD modulation and indications therefor | OPNA 生物公司 | 2024-04-30 | — | — | CN | disclosed |