Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 13/20 | 0.42 |
| ▸ | WEE1 | P30291 | 4/20 | 0.41 |
| ▸ | MYT1 | Q01538 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | HCK | P08631 | 1/20 | 0.36 |
| ▸ | FGR | P09769 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.36 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.36 |
| ▸ | ABL2 | P42684 | 1/20 | 0.36 |
| ▸ | BLK | P51451 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | EPHB1 | P54762 | 1/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27387964 | 1.00 | PKMYT1 (0.42) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL30971070 | 0.86 | GRM2 (0.39) | PKMYT1GRM2 | |
| SCHEMBL27387958 | 0.83 | PKMYT1 (0.41) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL30971207 | 0.83 | PKMYT1 (0.41) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL20674243 | 0.81 | LCK (0.41) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL30971169 | 0.79 | NQO2 (0.41) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL30971073 | 0.79 | PKMYT1 (0.39) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL27388046 | 0.79 | PKMYT1 (0.39) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL27388056 | 0.79 | NQO2 (0.41) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL27397482 | 0.77 | GRM2 (0.63) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |