Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30434181 | 0.76 | CYP2A6 (0.40) | TDP1 | |
| SCHEMBL26973210 | 0.65 | KMT2A (0.30) | — | |
| SCHEMBL10321593 | 0.61 | — | — | |
| SCHEMBL29549774 | 0.61 | — | — | |
| SCHEMBL26973212 | 0.60 | TDP1 (0.30) | TDP1 | |
| Ammonia Solution, Strong SCHEMBL26650853 | 0.60 | TDP1 (0.30) | TDP1 | |
| Ammonia Solution, Strong SCHEMBL31373461 | 0.60 | TDP1 (0.30) | TDP1 | |
| SCHEMBL17703504 | 0.58 | — | — | |
| SCHEMBL11308803 | 0.57 | HSD17B10 (0.50) | TDP1 | |
| SCHEMBL27014225 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145623-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |