Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | IARS1 | P41252 | 1/20 | 0.30 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | MARS1 | P56192 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24917230 | 0.89 | TMPRSS2 (0.50) | TMPRSS2EGLN2 | |
| SCHEMBL24917594 | 0.88 | TMPRSS2 (0.61) | TMPRSS2MGLLEGLN2 | |
| SCHEMBL24917254 | 0.88 | TMPRSS2 (0.49) | TMPRSS2EGLN2 | |
| SCHEMBL30973716 | 0.88 | TMPRSS2 (0.41) | TMPRSS2IARS1 | |
| SCHEMBL25912266 | 0.87 | TMPRSS2 (0.49) | TMPRSS2IARS1EGLN2MARS1 | |
| SCHEMBL31660950 | 0.87 | TMPRSS2 (0.41) | TMPRSS2 | |
| SCHEMBL24789770 | 0.87 | TMPRSS2 (0.48) | TMPRSS2 | |
| SCHEMBL30973789 | 0.86 | TMPRSS2 (0.49) | TMPRSS2 | |
| SCHEMBL24789427 | 0.86 | TMPRSS2 (0.50) | TMPRSS2IARS1MARS1 | |
| SCHEMBL30472930 | 0.86 | TMPRSS2 (0.50) | TMPRSS2IARS1MARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129963-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. (US) | 2024-06-20 | — | — | WO | disclosed |