Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26136509 | 0.93 | TMPRSS2 (0.60) | TMPRSS2ALDH1A1EGLN2ADORA3 | |
| SCHEMBL24917209 | 0.93 | TMPRSS2 (0.60) | TMPRSS2ALDH1A1EGLN2ADORA3 | |
| SCHEMBL25909937 | 0.91 | TMPRSS2 (0.59) | TMPRSS2ALDH1A1HTTEGLN2ADORA3 | |
| SCHEMBL24791240 | 0.90 | TMPRSS2 (0.61) | TMPRSS2ALDH1A1HTTEGLN2ADORA3 | |
| SCHEMBL24917569 | 0.90 | TMPRSS2 (0.63) | TMPRSS2ALDH1A1EGLN2ADORA3 | |
| SCHEMBL26136380 | 0.90 | TMPRSS2 (0.63) | TMPRSS2ALDH1A1EGLN2ADORA3 | |
| SCHEMBL24791233 | 0.90 | TMPRSS2 (0.59) | TMPRSS2 | |
| SCHEMBL24917096 | 0.88 | TMPRSS2 (0.59) | TMPRSS2EGLN2ADORA3 | |
| SCHEMBL30973758 | 0.87 | TMPRSS2 (0.50) | TMPRSS2HTT | |
| SCHEMBL24789441 | 0.87 | TMPRSS2 (0.60) | TMPRSS2ALDH1A1EGLN2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129963-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. (US) | 2024-06-20 | — | — | WO | disclosed |