Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994208 | 0.91 | MAPT (0.53) | MAPTKDM4EALDH1A1PLA2G10TP53 | |
| SCHEMBL12076862 | 0.84 | MAPT (0.44) | MAPTPLA2G10TP53LMNATHRB | |
| SCHEMBL2989938 | 0.79 | MAPT (0.57) | MAPTKDM4EALDH1A1PLA2G10TP53 | |
| SCHEMBL3000527 | 0.78 | MAPT (0.49) | MAPTKDM4EALDH1A1PLA2G10TP53 | |
| SCHEMBL3000523 | 0.78 | MAPT (0.49) | MAPTKDM4EALDH1A1PLA2G10TP53 | |
| SCHEMBL2990636 | 0.78 | PLA2G10 (0.42) | MAPTKDM4EALDH1A1PLA2G10TP53 | |
| SCHEMBL2994393 | 0.76 | MAPT (0.49) | MAPTKDM4EALDH1A1PLA2G10TP53 | |
| SCHEMBL2997457 | 0.76 | SERPINE1 (0.60) | MAPTKDM4EALDH1A1PLA2G10TP53 | |
| SCHEMBL2987596 | 0.76 | PLA2G10 (0.42) | MAPTKDM4EALDH1A1PLA2G10TP53 | |
| SCHEMBL2988545 | 0.75 | MAPT (0.47) | MAPTKDM4EALDH1A1PLA2G10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678823-B2 | N-phenylindoles; oral dosage forms; side effect reduction | Myriad Pharmaceticals, Inc. (US) | 2010-03-16 | — | — | US | disclosed |