Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.54 |
| ▸ | REN | P00797 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PEPD | P12955 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30069169 | 0.93 | ACE (0.62) | ACERENKDM4EF2LMNA | |
| SCHEMBL30193349 | 0.84 | ACE (0.64) | ACERENKDM4EF2LMNA | |
| SCHEMBL14199456 | 0.84 | CAPN1 (0.47) | ACERENCALCRLCAPN1SLC6A2 | |
| SCHEMBL9614758 | 0.84 | CAPN1 (0.57) | ACERENCALCRLCAPN1SLC6A2 | |
| SCHEMBL9614754 | 0.84 | CAPN1 (0.57) | ACERENCALCRLCAPN1SLC6A2 | |
| SCHEMBL29576508 | 0.84 | CAPN1 (0.47) | ACERENCALCRLCAPN1XIAP | |
| SCHEMBL29530605 | 0.82 | XIAP (0.49) | ACERENCALCRLCAPN1XIAP | |
| SCHEMBL30997407 | 0.82 | CAPN1 (0.53) | ACERENKDM4EF2LMNA | |
| SCHEMBL31412187 | 0.82 | ACE (0.59) | ACERENKDM4EF2LMNA | |
| SCHEMBL30957276 | 0.81 | ACE (0.60) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132726-A1 | SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE | UNIWERSYTET GDANSKI (PL) | 2024-06-27 | — | — | WO | claimed |