Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 8/20 | 0.53 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | RAMP3 | O60896 | 3/20 | 0.41 |
| ▸ | CALCR | P30988 | 3/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30973997 | 0.90 | CAPN1 (0.55) | CAPN1NTSR1CTSBSLC6A2GRB2 | |
| SCHEMBL29569659 | 0.88 | CAPN1 (0.51) | CAPN1NTSR1CTSBGRB2RAMP3 | |
| SCHEMBL30973955 | 0.87 | SLC6A2 (0.60) | NTSR1SLC6A2APLNR | |
| SCHEMBL31433277 | 0.85 | CAPN1 (0.42) | CAPN1NTSR1SLC6A2GRB2APLNR | |
| SCHEMBL31433187 | 0.84 | MAPK8 (0.43) | CAPN1NTSR1GRB2APLNRCTSD | |
| SCHEMBL30420753 | 0.84 | GRB2 (0.47) | CAPN1NTSR1GRB2APLNRRAMP3 | |
| SCHEMBL31433348 | 0.83 | CALCR (0.45) | CAPN1NTSR1GRB2APLNRCALCR | |
| SCHEMBL31276263 | 0.83 | CAPN1 (0.51) | CAPN1NTSR1APLNRCTSDBACE1 | |
| SCHEMBL31433333 | 0.83 | CALCR (0.46) | CAPN1NTSR1APLNRCALCR | |
| SCHEMBL30059762 | 0.82 | SLC6A2 (0.50) | CAPN1NTSR1CTSBSLC6A2GRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132726-A1 | SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE | UNIWERSYTET GDANSKI (PL) | 2024-06-27 | — | — | WO | disclosed |