SCHEMBL30974284

C[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)[C@@H](C)O)[C@@H](C)O

nearest known ligand 0.46

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	15/20	0.46

▸	SCTR	P47872	1/20	0.46

▸	KEAP1	Q14145	1/20	0.43

▸	CRHR1	P34998	1/20	0.43

▸	CRHR2	Q13324	1/20	0.43

▸	GCGR	P47871	1/20	0.42

▸	CALCR	P30988	2/20	0.42

▸	OPRM1	P35372	1/20	0.41

▸	OPRD1	P41143	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30974471	0.96	GLP1R (0.46)	GLP1RSCTRKEAP1CRHR1CRHR2
SCHEMBL30974417	0.94	GLP1R (0.49)	GLP1RSCTRCRHR1CRHR2GCGR
SCHEMBL30974371	0.93	GLP1R (0.45)	GLP1RSCTRKEAP1CRHR1CRHR2
SCHEMBL31741239	0.90	GLP1R (0.55)	GLP1RSCTRGCGR
SCHEMBL30974081	0.90	GLP1R (0.49)	GLP1RSCTRCRHR1CRHR2GCGR
SCHEMBL30312252	0.89	GLP1R (0.45)	GLP1RSCTRKEAP1CALCR
SCHEMBL31740815	0.88	GLP1R (0.56)	GLP1RSCTRGCGR
SCHEMBL30974194	0.88	GLP1R (0.49)	GLP1RSCTRCRHR1CRHR2GCGR
SCHEMBL30124627	0.88	GLP1R (0.40)	GLP1RSCTROPRM1OPRD1
SCHEMBL30588169	0.87	GLP1R (0.43)	GLP1RSCTRKEAP1CALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024132726-A1	SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE	UNIWERSYTET GDANSKI (PL)	2024-06-27	—	—	WO	disclosed