SCHEMBL30974406

CC(C)C[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.55

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	9/20	0.55

▸	CALCR	P30988	9/20	0.55

▸	KDM1A	O60341	2/20	0.50

▸	NPY2R	P49146	7/20	0.49

▸	NPY4R	P50391	7/20	0.49

▸	NPY5R	Q15761	7/20	0.49

▸	NPY1R	P25929	5/20	0.49

▸	MAPK8	P45983	1/20	0.49

▸	MAPK9	P45984	1/20	0.49

▸	MAPK10	P53779	1/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30974226	0.91	RAMP3 (0.50)	RAMP3CALCRKDM1AMAPK8MAPK9
SCHEMBL30974402	0.91	NPY2R (0.55)	RAMP3CALCRKDM1ANPY2RNPY4R
SCHEMBL29611483	0.90	MAPK8 (0.51)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL29679575	0.90	RAMP3 (0.52)	RAMP3CALCRKDM1A
SCHEMBL30974082	0.90	RAMP3 (0.55)	RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL30974597	0.89	RAMP3 (0.68)	RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL30974349	0.89	RAMP3 (0.69)	RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL30991505	0.88	KDM1A (0.50)	RAMP3CALCRKDM1ANPY2RNPY4R
SCHEMBL30429358	0.87	NPY2R (0.59)	RAMP3CALCRKDM1ANPY2RNPY4R
SCHEMBL31399668	0.87	RAMP3 (0.52)	RAMP3CALCRKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024132726-A1	SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE	UNIWERSYTET GDANSKI (PL)	2024-06-27	—	—	WO	disclosed