Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 5/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30123047 | 1.00 | PDCD1LG2 (0.48) | PDCD1LG2CD274MMEACECPA1 | |
| SCHEMBL30123330 | 0.95 | PDCD1LG2 (0.45) | PDCD1LG2CD274MMEACECPA1 | |
| SCHEMBL30118062 | 0.89 | BACE1 (0.44) | PDCD1LG2CD274MMEACECPA1 | |
| SCHEMBL30781147 | 0.88 | MME (0.47) | PDCD1LG2CD274MMEACECPA1 | |
| SCHEMBL29531322 | 0.88 | MME (0.47) | PDCD1LG2CD274MMEACECPA1 | |
| SCHEMBL23030200 | 0.88 | MME (0.47) | PDCD1LG2CD274MMEACECPA1 | |
| SCHEMBL5841680 | 0.88 | MME (0.47) | PDCD1LG2CD274MMEACECPA1 | |
| SCHEMBL5841678 | 0.88 | MME (0.47) | PDCD1LG2CD274MMEACECPA1 | |
| SCHEMBL29840628 | 0.87 | CD274 (0.54) | PDCD1LG2CD274MMEDPP4DPP8 | |
| SCHEMBL31307923 | 0.87 | PDCD1LG2 (0.47) | PDCD1LG2CD274MMECTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132726-A1 | SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE | UNIWERSYTET GDANSKI (PL) | 2024-06-27 | — | — | WO | disclosed |