Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481437 | 0.90 | NPSR1 (0.45) | NPSR1CYP4F2CYP4A11CYP3A4TSHR | |
| SCHEMBL6136955 | 0.82 | NPSR1 (0.34) | NPSR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17869535 | 0.80 | NPSR1 (0.35) | NPSR1 | |
| SCHEMBL14809324 | 0.78 | NPSR1 (0.36) | NPSR1 | |
| SCHEMBL25973904 | 0.77 | NPSR1 (0.48) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 | |
| SCHEMBL29246996 | 0.76 | NPSR1 (0.36) | NPSR1 | |
| SCHEMBL2775123 | 0.74 | NPSR1 (0.50) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 | |
| SCHEMBL19359199 | 0.74 | NPSR1 (0.32) | NPSR1TSHR | |
| SCHEMBL3375373 | 0.72 | NPSR1 (0.44) | NPSR1CYP4F2CYP4A11CYP3A4ALDH1A1 | |
| SCHEMBL16234619 | 0.71 | CYP3A4 (0.42) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317963-A | TRPML modulators, compositions thereof, and methods of use | 卡拉韦治疗公司 | 2024-07-09 | — | — | CN | disclosed |