Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | NNMT | P40261 | 5/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1939828 | 0.79 | PIP4K2A (0.44) | PRMT5WDR77SLC22A12SRCNNMT | |
| SCHEMBL30372781 | 0.78 | PIP4K2A (0.39) | PRMT5WDR77SLC22A12NNMTFGFR1 | |
| SCHEMBL29246916 | 0.78 | PIP4K2A (0.39) | PRMT5WDR77SLC22A12NNMTFGFR1 | |
| SCHEMBL17877686 | 0.77 | PIP4K2A (0.44) | PRMT5WDR77SLC22A12SRCNNMT | |
| SCHEMBL16769943 | 0.76 | SLC22A12 (0.40) | PRMT5WDR77SLC22A12NNMTFGFR1 | |
| SCHEMBL24753099 | 0.76 | PIP4K2A (0.44) | PRMT5WDR77SLC22A12SRCHRH3 | |
| SCHEMBL16967987 | 0.75 | PIP4K2A (0.49) | PRMT5WDR77SLC22A12SRCFGFR1 | |
| SCHEMBL21682107 | 0.72 | PRMT5 (0.39) | PRMT5WDR77SLC22A12NNMTFGFR1 | |
| SCHEMBL21682109 | 0.72 | PRMT5 (0.39) | PRMT5WDR77SLC22A12NNMTFGFR1 | |
| SCHEMBL16139203 | 0.72 | CYP2C19 (0.47) | PRMT5WDR77SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317963-A | TRPML modulators, compositions thereof, and methods of use | 卡拉韦治疗公司 | 2024-07-09 | — | — | CN | disclosed |