Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22152010 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2GAAAAK1IMPDH2NPSR1 | |
| SCHEMBL22122364 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2GAAIMPDH2NPSR1POLB | |
| SCHEMBL22122243 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAIMPDH2NPSR1POLB | |
| SCHEMBL22152011 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2GAAAAK1IMPDH2NPSR1 | |
| SCHEMBL30975237 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2GAAAAK1IMPDH2NPSR1 | |
| SCHEMBL22122212 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2GAAAAK1IMPDH2NPSR1 | |
| SCHEMBL22122433 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2GAAIMPDH2NPSR1POLB | |
| SCHEMBL28657765 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAAAK1IMPDH2NPSR1 | |
| SCHEMBL22122214 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2GAAIMPDH2NPSR1POLB | |
| SCHEMBL22122211 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAIMPDH2NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240139185-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2024-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240139185-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | KRAS, NRAS, HRAS | SMN1; SMN2 4348/4885GAA 3216/4885AAK1 1505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.