SCHEMBL30975754

SCHEMBL30975754

CS(=N)(=O)c1cc(NC(=O)c2c(C(F)(F)F)c(C3CC3)nn2CC2C(F)(F)C23CC3)ccn1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCN10A Q9Y5Y9 20/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30975743 0.97 SCN10A (0.43) SCN10A
SCHEMBL30975753 0.95 SCN10A (0.43) SCN10A
SCHEMBL30975609 0.89 SCN10A (0.41) SCN10A
SCHEMBL30975725 0.88 SCN10A (0.43) SCN10A
SCHEMBL30975653 0.87 SCN10A (0.41) SCN10A
SCHEMBL30975955 0.87 SCN10A (0.43) SCN10A
SCHEMBL30975622 0.87 SCN10A (0.43) SCN10A
SCHEMBL30975836 0.87 SCN10A (0.43) SCN10A
SCHEMBL30975638 0.87 SCN10A (0.41) SCN10A
SCHEMBL30975703 0.87 SCN10A (0.41) SCN10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634159-A1 SULFOXIMINES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2025-10-22 EP claimed
WO-2024126648-A1 SULFOXIMINES AS INHIBITORS OF NaV1.8 Grünenthal GmbH (DE) 2024-06-20 WO claimed
EP-4634159-A1 SULFOXIMINES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2025-10-22 EP disclosed
WO-2024126648-A1 SULFOXIMINES AS INHIBITORS OF NaV1.8 Grünenthal GmbH (DE) 2024-06-20 WO disclosed