SCHEMBL30975795

SCHEMBL30975795

CC1(Cn2nc(C3CC3)c(C(F)(F)F)c2C(=O)Nc2ccnc(S(C)(=N)=O)c2)CCC(F)(F)C1

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCN10A Q9Y5Y9 20/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30975737 0.95 SCN10A (0.44) SCN10A
SCHEMBL30975981 0.95 SCN10A (0.44) SCN10A
SCHEMBL30975776 0.92 SCN10A (0.43) SCN10A
SCHEMBL30975786 0.92 SCN10A (0.43) SCN10A
SCHEMBL30975767 0.91 SCN10A (0.42) SCN10A
SCHEMBL30975739 0.91 SCN10A (0.41) SCN10A
SCHEMBL30975803 0.90 SCN10A (0.40) SCN10A
SCHEMBL30975748 0.89 SCN10A (0.43) SCN10A
SCHEMBL30975780 0.89 SCN10A (0.39) SCN10A
SCHEMBL30975724 0.89 SCN10A (0.41) SCN10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634159-A1 SULFOXIMINES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2025-10-22 EP claimed
WO-2024126648-A1 SULFOXIMINES AS INHIBITORS OF NaV1.8 Grünenthal GmbH (DE) 2024-06-20 WO claimed
EP-4634159-A1 SULFOXIMINES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2025-10-22 EP disclosed
WO-2024126648-A1 SULFOXIMINES AS INHIBITORS OF NaV1.8 Grünenthal GmbH (DE) 2024-06-20 WO disclosed