⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976029 | 0.90 | — | — | |
| SCHEMBL30975892 | 0.88 | — | — | |
| SCHEMBL30975843 | 0.87 | — | — | |
| SCHEMBL30975858 | 0.87 | — | — | |
| SCHEMBL30976050 | 0.86 | SLC10A1 (0.31) | — | |
| SCHEMBL30975865 | 0.86 | PTGER4 (0.30) | — | |
| SCHEMBL30976001 | 0.86 | PTGDR2 (0.31) | — | |
| SCHEMBL30975845 | 0.85 | SLC10A1 (0.31) | — | |
| SCHEMBL30975882 | 0.82 | — | — | |
| SCHEMBL27417449 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634159-A1 | SULFOXIMINES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024126648-A1 | SULFOXIMINES AS INHIBITORS OF NaV1.8 | Grünenthal GmbH (DE) | 2024-06-20 | — | — | WO | disclosed |