Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.54 |
| ▸ | GAPDH | P04406 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TK1 | P04183 | 1/20 | 0.45 |
| ▸ | TK2 | O00142 | 2/20 | 0.44 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | HRAS | P01112 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591286 | 0.96 | MEN1 (0.61) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL5983740 | 0.96 | MEN1 (0.61) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL1882384 | 0.96 | MEN1 (0.61) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL9223575 | 0.96 | MEN1 (0.61) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL21886712 | 0.96 | MEN1 (0.61) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL14428953 | 0.95 | MEN1 (0.60) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL16907939 | 0.92 | MEN1 (0.56) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL19132202 | 0.92 | MEN1 (0.56) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL9131765 | 0.92 | MEN1 (0.56) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL15691494 | 0.92 | MEN1 (0.56) | MEN1USP2POLBKMT2ARNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107850-A1 | HALO-DEHYDRO-3'-DEOXYURACIL PHOSPHORAMIDATES AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ROME THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |