Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 4/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.31 |
| ▸ | KDR | P35968 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979109 | 0.83 | PDE5A (0.37) | PDE5ACDK2GSK3BDYRK1AEGFR | |
| SCHEMBL29909866 | 0.83 | PDE5A (0.37) | PDE5ACDK2GSK3BDYRK1AEGFR | |
| SCHEMBL29909864 | 0.82 | PDE5A (0.40) | PDE5ACDK2GSK3BDYRK1AEGFR | |
| SCHEMBL29210703 | 0.82 | PDE5A (0.40) | PDE5ACDK2GSK3BDYRK1AEGFR | |
| SCHEMBL30978997 | 0.82 | PDE5A (0.36) | PDE5ACDK2GSK3BDYRK1AEGFR | |
| SCHEMBL30979122 | 0.76 | PDE5A (0.43) | PDE5AEGFRABCG2CSNK2A2CSNK2B | |
| SCHEMBL30978980 | 0.76 | PDE5A (0.43) | PDE5ACDK2GSK3BDYRK1AEGFR | |
| SCHEMBL29213130 | 0.76 | PDE5A (0.43) | PDE5ACDK2GSK3BDYRK1AEGFR | |
| SCHEMBL30979027 | 0.74 | PDE5A (0.41) | PDE5AEGFR | |
| SCHEMBL30979143 | 0.74 | PDE5A (0.41) | PDE5ACDK2GSK3BDYRK1AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |