Sugi Predict

Sugi Predict / Compounds / SCHEMBL30979322

SCHEMBL30979322

SCHEMBL30979322

Cc1nc2c(Br)cc(CO)cc2[nH]c1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PARP1 P09874 5/20 0.37
▸ RNASEH1 O60930 1/20 0.36
▸ NQO2 P16083 1/20 0.36
▸ GRIA1 P42261 1/20 0.35
▸ GRIA2 P42262 1/20 0.35
▸ GRIA3 P42263 1/20 0.35
▸ GRIA4 P48058 1/20 0.35
▸ GRIN2D O15399 1/20 0.34
▸ GRIN3B O60391 1/20 0.34
▸ GRIN1 Q05586 1/20 0.34
▸ GRIN2A Q12879 1/20 0.34
▸ GRIN2B Q13224 1/20 0.34
▸ GRIN2C Q14957 1/20 0.34
▸ GRIN3A Q8TCU5 1/20 0.34
▸ LMNA P02545 2/20 0.33
▸ HPGD P15428 2/20 0.33
▸ DAO P14920 1/20 0.33
▸ MAOA P21397 1/20 0.33
▸ DYRK1A Q13627 1/20 0.33
▸ NSD2 O96028 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30979321 0.87 GRIN2D (0.35) PARP1RNASEH1NQO2GRIN2DGRIN3B
SCHEMBL30979344 0.82 HTT (0.41) PARP1RNASEH1GRIA1GRIA2GRIA3
SCHEMBL30979325 0.82 PARP1 (0.50) PARP1GRIA1GRIA2GRIA3GRIA4
SCHEMBL16053516 0.80 GRIN2D (0.42) PARP1NQO2GRIN2DGRIN3BGRIN1
SCHEMBL31424804 0.78 DHODH (0.41) PARP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL31424785 0.78 PARP1 (0.38) PARP1GRIA1GRIA2GRIA3GRIA4
SCHEMBL31424567 0.78 HSD17B10 (0.38) PARP1LMNAHPGDDAOMAOA
SCHEMBL31426133 0.77 NSD2 (0.36) NQO2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL31424608 0.77 PARP1 (0.37) PARP1GRIA1GRIA2GRIA3GRIA4
SCHEMBL31424760 0.76 PARP1 (0.36) PARP1GRIA1GRIA2GRIA3GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346573-A1 AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF CHENGDU EASTON BIOPHARMACEUTICALS CO LTD (CN) 2025-11-13 — — US disclosed
CN-120020129-A Substituted nitrogen-containing bicyclic compounds and uses thereof 广东东阳光药业股份有限公司 2025-05-20 — — CN disclosed
EP-4534533-A1 AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF Chengdu Easton Biopharmaceuticals Co., Ltd. (CN) 2025-04-09 — — EP disclosed
CN-119431314-A Substituted nitrogen-containing bicyclic compounds and uses thereof 广东东阳光药业股份有限公司 2025-02-14 — — CN disclosed
CN-118076597-A Azaquinolinone derivative, preparation method and application thereof 成都苑东生物制药股份有限公司 2024-05-24 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346573-A1 AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF PARP1, PARP8, PARP11 PARP1 1/4885RNASEH1 887/4885NQO2 119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.