⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115888 | 1.00 | — | — | |
| SCHEMBL3098062 | 1.00 | — | — | |
| SCHEMBL13888940 | 1.00 | — | — | |
| SCHEMBL1821097 | 0.95 | TSHR (0.82) | — | |
| SCHEMBL11691617 | 0.95 | TSHR (0.82) | — | |
| SCHEMBL328907 | 0.95 | TSHR (0.82) | — | |
| SCHEMBL9225512 | 0.95 | TSHR (0.82) | — | |
| SCHEMBL9215694 | 0.91 | TSHR (0.91) | — | |
| SCHEMBL15832112 | 0.91 | TSHR (0.91) | — | |
| SCHEMBL11324930 | 0.91 | TSHR (0.91) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250368983-A1 | CONTROLLING FOR TAGMENTATION SEQUENCING LIBRARY INSERT SIZE USING ARCHAEAL HISTONE-LIKE PROTEINS | KAPA BIOSYSTEMS INC (US) | 2025-12-04 | — | — | US | disclosed |
| WO-2024046992-A1 | IMPROVEMENTS TO NEXT-GENERATION TARGET ENRICHMENT PERFORMANCE | F. HOFFMANN-LA ROCHE AG (CH) | 2024-03-07 | — | — | WO | disclosed |
| WO-2024003332-A1 | CONTROLLING FOR TAGMENTATION SEQUENCING LIBRARY INSERT SIZE USING ARCHAEAL HISTONE-LIKE PROTEINS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-01-04 | — | — | WO | disclosed |
| EP-3149446-B1 | FIXATIVE COMPOSITION FOR CELL-COMPRISING LIQUID SAMPLES | QIAGEN GMBH (DE) | 2022-07-06 | — | — | EP | disclosed |
| US-20210389216-A1 | FIXATION OF A BIOLOGICAL MATERIAL | QIAGEN GMBH (DE) | 2021-12-16 | — | — | US | disclosed |
| US-20210381937-A1 | FIXATION OF A BIOLOGICAL MATERIAL | QIAGEN GMBH (DE) | 2021-12-09 | — | — | US | disclosed |
| US-10794803-B2 | Fixative composition for cell-comprising liquid samples and methods and kit thereof | QIAGEN GMBH (DE) | 2020-10-06 | — | — | US | disclosed |
| US-20170052095-A1 | Fixative Composition for Cell-Comprising Liquid Samples | QIAGEN GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| EP-2126542-B1 | FIXATION OF A BIOLOGICAL MATERIAL | QIAGEN GMBH (DE) | 2016-11-02 | — | — | EP | disclosed |
| US-8796028-B2 | Method for treating a biological sample with a composition containing at least one polyol and excluding water | QIAGEN GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-20100173295-A1 | FIXATION OF A BIOLOGICAL MATERIAL | QIAGEN GMBH (DE) | 2010-07-08 | — | — | US | disclosed |
| US-20100009349-A1 | Method for Treating a Biological Sample | QIAGEN GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
| EP-2048167-A2 | First catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | Sumitomo Chemical Company, Limited (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-2048168-A2 | Process for producing catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | Sumitomo Chemical Company, Limited (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-2048169-A2 | Third catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | Sumitomo Chemical Company, Limited (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-1965190-A1 | Fixation of a biological sample | Qiagen GmbH (DE) | 2008-09-03 | — | — | EP | disclosed |