SCHEMBL30983801

SCHEMBL30983801

Cc1ccnc(Cn2c(-c3ccc(OC4CN(C(=O)OC(C)(C)C)C4)cc3Cl)nc3c(OC4(C)CC4)ncnc32)c1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 20/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30983810 0.91 PIK3CD (0.39) PIK3CD
SCHEMBL31269389 0.91 PIK3CD (0.41) PIK3CD
SCHEMBL31268814 0.91 PIK3CD (0.38) PIK3CD
SCHEMBL31268882 0.90 PIK3CD (0.38) PIK3CD
SCHEMBL30984003 0.90 PIK3CD (0.38) PIK3CD
SCHEMBL31269216 0.89 PIK3CD (0.37) PIK3CD
SCHEMBL31268893 0.89 PIK3CD (0.37) PIK3CD
SCHEMBL31269039 0.88 PIK3CD (0.43) PIK3CD
SCHEMBL30984031 0.88 PIK3CD (0.36) PIK3CD
SCHEMBL31269209 0.87 PIK3CD (0.43) PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630410-A1 POLQ INHIBITORS Astrazeneca AB (SE) 2025-10-15 — — EP disclosed
WO-2024121753-A1 POLQ INHIBITORS ASTRAZENECA AB (SE) 2024-06-13 — — WO disclosed
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