Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.70 |
| ▸ | PI4KA | P42356 | 1/20 | 0.70 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.70 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.70 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.70 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.59 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980291 | 1.00 | ADORA2A (0.70) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5459069 | 0.88 | DAPK1 (0.67) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8174343 | 0.85 | HDAC6 (0.70) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL6659705 | 0.84 | HDAC6 (0.62) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5453774 | 0.84 | HDAC6 (0.62) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL28781461 | 0.83 | HDAC6 (0.51) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30586358 | 0.83 | ADORA2A (0.68) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| 9-Benzyl-9H-Adenine SCHEMBL104932 | 0.83 | ADORA2A (1.00) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2979897 | 0.83 | ADORA2A (0.68) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL4346676 | 0.83 | ADORA2A (0.68) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| CN-118638119-B | Pyrazole purine herbicide safener as well as preparation method and application thereof | 东北农业大学 | 2025-02-28 | — | — | CN | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |
| CN-118638119-A | Pyrazole purine herbicide safener as well as preparation method and application thereof | 东北农业大学 | 2024-09-13 | — | — | CN | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |