SCHEMBL30984030

SCHEMBL30984030

CC(C)(C)OC(=O)N1CCN(CCOc2ccc(-c3nc4c(OC5CC5)ncnc4n3Cc3cccc(Cl)c3)c(Cl)c2)CC1

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 17/20 0.45
▸ CNR1 P21554 2/20 0.42
▸ CNR2 P34972 2/20 0.42
▸ ADORA2A P29274 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30983947 0.90 ADORA2A (0.45) CNR1CNR2ADORA2A
SCHEMBL30983875 0.89 CNR1 (0.41) PIK3CDCNR1CNR2ADORA2A
SCHEMBL30983922 0.87 CNR1 (0.39) PIK3CDCNR1CNR2ADORA2A
SCHEMBL30984010 0.86 CNR1 (0.43) PIK3CDCNR1CNR2ADORA2A
SCHEMBL30983385 0.85 KDM4E (0.42) CNR1
SCHEMBL30983846 0.85 CNR1 (0.47) CNR1CNR2ADORA2A
SCHEMBL30983802 0.84 CNR1 (0.43) PIK3CDCNR1CNR2
SCHEMBL30984027 0.83 CNR1 (0.42) PIK3CDCNR1CNR2
SCHEMBL30984074 0.82 CNR1 (0.42) PIK3CDCNR1CNR2
SCHEMBL30983785 0.82 CNR1 (0.41) PIK3CDCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
EP-4630410-A1 POLQ INHIBITORS Astrazeneca AB (SE) 2025-10-15 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
WO-2024121753-A1 POLQ INHIBITORS ASTRAZENECA AB (SE) 2024-06-13 — — WO disclosed
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