Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 1/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984300 | 0.95 | WRN (0.58) | WRNPIK3CDPIK3C2BPIK3CGWDR5 | |
| SCHEMBL30984106 | 0.93 | WRN (0.54) | WRNPIK3CDPIK3C2BPIK3CGWDR5 | |
| SCHEMBL25035210 | 0.93 | WRN (0.61) | WRNPIK3CDPIK3C2BPIK3CGWDR5 | |
| SCHEMBL30984202 | 0.91 | WRN (0.57) | WRNPIK3CDPIK3C2BPIK3CGWDR5 | |
| SCHEMBL30037645 | 0.90 | WRN (0.61) | WRNPIK3CDPIK3C2BPIK3CGWDR5 | |
| SCHEMBL25037112 | 0.90 | WRN (0.61) | WRNPIK3CDPIK3C2BPIK3CGWDR5 | |
| SCHEMBL30984138 | 0.90 | WRN (0.63) | WRNPIK3CDPIK3C2BPIK3CG | |
| SCHEMBL25037344 | 0.89 | WRN (0.70) | WRNGAA | |
| SCHEMBL30038062 | 0.89 | WRN (0.70) | WRNGAA | |
| SCHEMBL30984287 | 0.88 | WRN (0.55) | WRNWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153155-A1 | DOUBLE-HETEROCYCLIC WRN INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 成都微芯药业有限公司 | 2024-07-25 | — | — | WO | disclosed |