Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.57 |
| ▸ | ESR1 | P03372 | 7/20 | 0.54 |
| ▸ | IKZF2 | Q9UKS7 | 6/20 | 0.49 |
| ▸ | WIZ | O95785 | 1/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985105 | 0.97 | CRBN (0.57) | CRBNESR1IKZF2WIZIKZF1 | |
| SCHEMBL30984743 | 0.94 | CRBN (0.59) | CRBNESR1IKZF2WIZIKZF1 | |
| SCHEMBL30984796 | 0.90 | CRBN (0.64) | CRBNESR1IKZF2WIZIKZF1 | |
| SCHEMBL30985245 | 0.90 | CRBN (0.53) | CRBNESR1IKZF2WIZIKZF1 | |
| SCHEMBL30253895 | 0.89 | CRBN (0.54) | CRBNESR1IKZF2WIZIKZF1 | |
| SCHEMBL30984840 | 0.87 | CRBN (0.57) | CRBNESR1IKZF2WIZ | |
| SCHEMBL30985037 | 0.87 | CRBN (0.54) | CRBNESR1IKZF2WIZIKZF1 | |
| SCHEMBL26609331 | 0.86 | IKZF2 (0.53) | CRBNESR1IKZF2WIZIKZF1 | |
| SCHEMBL26609576 | 0.86 | IKZF2 (0.55) | CRBNESR1IKZF2WIZ | |
| SCHEMBL25208119 | 0.85 | CRBN (0.52) | CRBNESR1IKZF2WIZIKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |