Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20235035 | 0.93 | CRBN (0.56) | CRBNIKZF2 | |
| SCHEMBL24501883 | 0.87 | CRBN (0.58) | CRBNIKZF2 | |
| SCHEMBL20372613 | 0.87 | CRBN (0.58) | CRBNIKZF2 | |
| SCHEMBL29648403 | 0.87 | CRBN (0.58) | CRBNIKZF2 | |
| SCHEMBL20046719 | 0.86 | CRBN (0.65) | CRBN | |
| SCHEMBL30821190 | 0.86 | CRBN (0.65) | CRBN | |
| SCHEMBL26650996 | 0.86 | CRBN (0.65) | CRBN | |
| SCHEMBL29614518 | 0.86 | CRBN (0.65) | CRBN | |
| SCHEMBL31726743 | 0.86 | CRBN (0.65) | CRBN | |
| SCHEMBL30821193 | 0.86 | CRBN (0.65) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |