Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.62 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | IL1B | P01584 | 1/20 | 0.43 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985096 | 0.96 | CRBN (0.59) | CRBNIKZF2BRD4TNFIL1B | |
| SCHEMBL30984929 | 0.95 | CRBN (0.60) | CRBNIKZF2BRD4TNFIL1B | |
| SCHEMBL30984919 | 0.94 | CRBN (0.61) | CRBNIKZF2BRD4TNFIL1B | |
| SCHEMBL30984968 | 0.91 | CRBN (0.61) | CRBNIKZF2BRD4TNFIL1B | |
| SCHEMBL30985169 | 0.90 | CRBN (0.58) | CRBNIKZF2BRD4TNFIL1B | |
| SCHEMBL30985022 | 0.89 | CRBN (0.57) | CRBNIKZF2 | |
| SCHEMBL30984748 | 0.89 | CRBN (0.59) | CRBNIKZF2 | |
| SCHEMBL30984888 | 0.89 | CRBN (0.59) | CRBNIKZF2BRD4TNFIL1B | |
| SCHEMBL30984740 | 0.88 | CRBN (0.60) | CRBNIKZF2BRD4TNFIL1B | |
| SCHEMBL30984895 | 0.88 | CRBN (0.60) | CRBNIKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |